<?xml version="1.0" encoding="UTF-8"?>
<ONIXMessage release="3.0" xmlns="http://ns.editeur.org/onix/3.0/reference">
  <Header>
    <Sender>
      <SenderName>EDP Sciences</SenderName>
    </Sender>
    <MessageNumber>1781724181</MessageNumber>
    <SentDateTime>20260617</SentDateTime>
    <DefaultLanguageOfText>fre</DefaultLanguageOfText>
  </Header>
  <Product>
    <RecordReference>laboutique.edpsciences.fr-R002862</RecordReference>
    <NotificationType>03</NotificationType>
    <RecordSourceType>01</RecordSourceType>
    <ProductIdentifier>
      <ProductIDType>01</ProductIDType>
      <IDValue>R002862</IDValue>
    </ProductIdentifier>
    <DescriptiveDetail>
      <ProductComposition>00</ProductComposition>
      <ProductForm>ED</ProductForm>
      <ProductFormDetail>E107</ProductFormDetail>
      <EpubTechnicalProtection>00</EpubTechnicalProtection>
      <TitleDetail>
        <TitleType>01</TitleType>
        <TitleElement>
          <TitleElementLevel>01</TitleElementLevel>
          <TitleText>Synthetic Biology Roadmap 2030 </TitleText>
          <Subtitle>The Engine of Next-Generation Biomanufacturing</Subtitle>
        </TitleElement>
      </TitleDetail>
      <Language>
        <LanguageRole>01</LanguageRole>
        <LanguageCode>eng</LanguageCode>
      </Language>
      <Extent>
        <ExtentType>08</ExtentType>
        <ExtentValue>346</ExtentValue>
        <ExtentUnit>03</ExtentUnit>
      </Extent>
      <Extent>
        <ExtentType>22</ExtentType>
        <ExtentValue>29053258</ExtentValue>
        <ExtentUnit>17</ExtentUnit>
      </Extent>
    </DescriptiveDetail>
    <CollateralDetail>
    </CollateralDetail>
    <PublishingDetail>
      <Imprint>
        <ImprintIdentifier>
          <ImprintIDType>01</ImprintIDType>
          <IDValue>P15</IDValue>
        </ImprintIdentifier>
        <ImprintName>EDP Sciences &amp; Science Press</ImprintName>
      </Imprint>
      <Publisher>
        <PublishingRole>01</PublishingRole>
        <PublisherIdentifier>
          <PublisherIDType>01</PublisherIDType>
          <IDValue>P15</IDValue>
        </PublisherIdentifier>
        <PublisherName>EDP Sciences &amp; Science Press</PublisherName>
      </Publisher>
      <PublishingDate>
        <PublishingDateRole>11</PublishingDateRole>
        <DateFormat>00</DateFormat>
        <Date>20260617</Date>
      </PublishingDate>
    </PublishingDetail>
    <RelatedMaterial>
      <RelatedProduct>
        <ProductRelationCode>02</ProductRelationCode>
        <ProductIdentifier>
          <ProductIDType>01</ProductIDType>
          <IDValue>003040</IDValue>
        </ProductIdentifier>
        <ProductIdentifier>
          <ProductIDType>03</ProductIDType>
          <IDValue>9782759840564</IDValue>
        </ProductIdentifier>
        <ProductIdentifier>
          <ProductIDType>15</ProductIDType>
          <IDValue>9782759840564</IDValue>
        </ProductIdentifier>
      </RelatedProduct>
    </RelatedMaterial>
    <ProductSupply>
      <SupplyDetail>
        <Supplier>
          <SupplierRole>03</SupplierRole>
          <SupplierIdentifier>
            <SupplierIDType>01</SupplierIDType>
            <IDValue>D1</IDValue>
          </SupplierIdentifier>
          <SupplierName>EDP Sciences</SupplierName>
          <Website>
            <WebsiteRole>29</WebsiteRole>
            <WebsiteLink>https://laboutique.edpsciences.fr/open_access_download/3040/2862</WebsiteLink>
          </Website>
        </Supplier>
        <ProductAvailability>45</ProductAvailability>
        <UnpricedItemType>03</UnpricedItemType>
      </SupplyDetail>
    </ProductSupply>
  </Product>
  <Product>
    <RecordReference>laboutique.edpsciences.fr-003040</RecordReference>
    <NotificationType>03</NotificationType>
    <RecordSourceType>01</RecordSourceType>
    <ProductIdentifier>
      <ProductIDType>01</ProductIDType>
      <IDValue>003040</IDValue>
    </ProductIdentifier>
    <ProductIdentifier>
      <ProductIDType>03</ProductIDType>
      <IDValue>9782759840564</IDValue>
    </ProductIdentifier>
    <ProductIdentifier>
      <ProductIDType>15</ProductIDType>
      <IDValue>9782759840564</IDValue>
    </ProductIdentifier>
    <DescriptiveDetail>
      <ProductComposition>10</ProductComposition>
      <ProductForm>EA</ProductForm>
      <ProductFormDetail>E107</ProductFormDetail>
      <PrimaryContentType>10</PrimaryContentType>
      <EpubTechnicalProtection>00</EpubTechnicalProtection>
      <ProductPart>
        <ProductIdentifier>
          <ProductIDType>01</ProductIDType>
          <IDValue>R002862</IDValue>
        </ProductIdentifier>
        <ProductForm>ED</ProductForm>
        <ProductFormDetail>E107</ProductFormDetail>
        <NumberOfCopies>1</NumberOfCopies>
      </ProductPart>
      <Collection>
        <CollectionType>10</CollectionType>
        <TitleDetail>
          <TitleType>01</TitleType>
          <TitleElement>
            <TitleElementLevel>02</TitleElementLevel>
            <TitleText>Hors collection</TitleText>
            <Subtitle>-</Subtitle>
          </TitleElement>
        </TitleDetail>
      </Collection>
      <TitleDetail>
        <TitleType>01</TitleType>
        <TitleElement>
          <TitleElementLevel>01</TitleElementLevel>
          <TitleText>Synthetic Biology Roadmap 2030 </TitleText>
          <Subtitle>The Engine of Next-Generation Biomanufacturing</Subtitle>
        </TitleElement>
      </TitleDetail>
      <Contributor>
        <SequenceNumber>1</SequenceNumber>
        <ContributorRole>A01</ContributorRole>
        <NameIdentifier>
          <NameIDType>01</NameIDType>
          <IDValue>A2474</IDValue>
        </NameIdentifier>
        <PersonName>China Society of Biotechnology - Synthetic Biology Development Strategy Research Group -</PersonName>
        <PersonNameInverted>Synthetic Biology Development Strategy Research Group -, China Society of Biotechnology -</PersonNameInverted>
        <NamesBeforeKey>China Society of Biotechnology -</NamesBeforeKey>
        <KeyNames>Synthetic Biology Development Strategy Research Group -</KeyNames>
        <BiographicalNote></BiographicalNote>
      </Contributor>
      <Language>
        <LanguageRole>01</LanguageRole>
        <LanguageCode>eng</LanguageCode>
      </Language>
      <Extent>
        <ExtentType>08</ExtentType>
        <ExtentValue>340</ExtentValue>
        <ExtentUnit>03</ExtentUnit>
      </Extent>
      <Illustrated>01</Illustrated>
      <Subject>
        <SubjectSchemeIdentifier>20</SubjectSchemeIdentifier>
        <SubjectHeadingText>biology;biotechnology;Biomanufacturing;Bioeconomy</SubjectHeadingText>
      </Subject>
      <Subject>
        <SubjectSchemeIdentifier>10</SubjectSchemeIdentifier>
        <SubjectSchemeVersion>2011</SubjectSchemeVersion>
        <SubjectCode>SCI010000</SubjectCode>
      </Subject>
      <Subject>
        <SubjectSchemeIdentifier>29</SubjectSchemeIdentifier>
        <SubjectCode>CLIL4042</SubjectCode>
      </Subject>
      <Subject>
        <SubjectSchemeIdentifier>01</SubjectSchemeIdentifier>
        <SubjectCode>570</SubjectCode>
      </Subject>
      <AudienceCode>06</AudienceCode>
    </DescriptiveDetail>
    <CollateralDetail>
      <TextContent>
        <TextType>03</TextType>
        <ContentAudience>00</ContentAudience>
        <Text>&lt;p&gt;Synthetic biology has garnered widespread attention for its scientific merit and applicative value. It is regarded as a new paradigm in life science research (“build to learn”), and a core driving force for the iterative advancement of biotechnology and the transformative development of biomanufacturing (“build to use”). The techno-economic core thread of “Synthetic Biology – Biotechnology – Biomanufacturing – Bioeconomy is striking a new chord of the times for the common development of humanity.&lt;/p&gt;&lt;p&gt;Synthetic Biology Roadmap 2030 is the outcome of in-depth collaborative research by numerous scholars. Drawing fully upon relevant international roadmaps and strategic development reports, and integrating the latest advances in the field, it proposes for the first time a four-in-one disciplinary architecture for synthetic biology encompassing “theoretical connotations, enabling technologies, application prospects, and governance principles”, while rationally forecasting the development goals and implementation pathways to 2030.&lt;/p&gt;&lt;p&gt;As China’s contribution to the global landscape of synthetic biology roadmaps, this work will serve as a vital reference for research, education, technology transfer, public engagement, and public literacy in the field of synthetic biology. Furthermore, we hope it will provide decision-making support for national scientific research planning and deployment, disciplinary development and industrial growth of synthetic biology, empowering it to fuel new quality productive forces in biomanufacturing.&lt;/p&gt;</Text>
      </TextContent>
      <TextContent>
        <TextType>02</TextType>
        <ContentAudience>00</ContentAudience>
        <Text>&lt;p&gt;This book proposes a four-in-one disciplinary architecture for synthetic biology encompassing “theoretical connotations, enabling technologies, application prospects, and governance principles”, while rationally forecasting the development goals and implementation pathways to 2030.&lt;/p&gt;</Text>
      </TextContent>
      <TextContent>
        <TextType>04</TextType>
        <ContentAudience>00</ContentAudience>
        <Text>&lt;p&gt;1 Introduction ................................................................................................................. 1&lt;/p&gt;&lt;p&gt;2 Theoretical Framework .............................................................................................. 5&lt;/p&gt;&lt;p&gt;2.1 Multi-scale Modeling of Synthetic Biology ........................................................... 9&lt;/p&gt;&lt;p&gt;2.2 Artificial Intelligence for Synthetic Biology ........................................................ 29&lt;/p&gt;&lt;p&gt;3 Enabling Technologies .............................................................................................. 51&lt;/p&gt;&lt;p&gt;3.1 DNA Sequencing, Synthesis and Assembly ......................................................... 53&lt;/p&gt;&lt;p&gt;3.2 Gene Editing ........................................................................................................ 73&lt;/p&gt;&lt;p&gt;3.3 Protein Design ...................................................................................................... 89&lt;/p&gt;&lt;p&gt;3.4 Genetic Circuits................................................................................................... 111&lt;/p&gt;&lt;p&gt;3.5 Chassis Cells ...................................................................................................... 129&lt;/p&gt;&lt;p&gt;3.6 Cell-free Biosystems .......................................................................................... 147&lt;/p&gt;&lt;p&gt;3.7 Artificial Multicellular Systems ......................................................................... 161&lt;/p&gt;&lt;p&gt;3.8 Organoid Engineering ........................................................................................ 185&lt;/p&gt;&lt;p&gt;3.9 Unnatural Amino Acids Encoding and Synthetic Biosystems ........................... 201&lt;/p&gt;&lt;p&gt;3.10 Biotic-abiotic Hybrid Systems ......................................................................... 217&lt;/p&gt;&lt;p&gt;3.11 Biofoundry ....................................................................................................... 231&lt;/p&gt;&lt;p&gt;3.12 Biopart Data and Information Platforms .......................................................... 249&lt;/p&gt;&lt;p&gt;4 Application Prospects ............................................................................................. 263&lt;/p&gt;&lt;p&gt;4.1 De Novo Synthesis of Single Cells .................................................................... 265&lt;/p&gt;&lt;p&gt;4.2 Industrial Applications ....................................................................................... 283&lt;/p&gt;&lt;p&gt;4.3 Medical Applications ......................................................................................... 287&lt;/p&gt;&lt;p&gt;4.4 Agricultural and Future Food Applications ........................................................ 292&lt;/p&gt;&lt;p&gt;4.5 Environmental Applications ............................................................................... 296&lt;/p&gt;&lt;p&gt;4.6 Bio-Information Convergence Technology and Extraterrestrial Biology .......... 298&lt;/p&gt;&lt;p&gt;5 Guarantee Capability and Governance Principles .............................................. 303&lt;/p&gt;&lt;p&gt;5.1 Construction of Guarantee Capability ................................................................ 305&lt;/p&gt;&lt;p&gt;5.2 Governance Principles ........................................................................................311&lt;/p&gt;&lt;p&gt;5.3 Summary ............................................................................................................ 316&lt;/p&gt;&lt;p&gt;Appendix: Glossary of Terms ...................................................................................... 317&lt;/p&gt;</Text>
      </TextContent>
      <SupportingResource>
        <ResourceContentType>21</ResourceContentType>
        <ContentAudience>00</ContentAudience>
        <ResourceMode>06</ResourceMode>
        <ResourceVersion>
          <ResourceForm>01</ResourceForm>
          <ResourceLink>https://laboutique.edpsciences.fr/produit/1581/9782759840564/synthetic-biology-roadmap-2030</ResourceLink>
        </ResourceVersion>
      </SupportingResource>
      <SupportingResource>
        <ResourceContentType>01</ResourceContentType>
        <ContentAudience>00</ContentAudience>
        <ResourceMode>03</ResourceMode>
        <ResourceVersion>
          <ResourceForm>02</ResourceForm>
          <ResourceLink>https://laboutique.edpsciences.fr/system/product_pictures/data/009/983/636/original/9782759840526-Synthetic_Biology_Roadmap_2030_couv-sofedis.jpg</ResourceLink>
          <ContentDate>
            <ContentDateRole>17</ContentDateRole>
            <DateFormat>14</DateFormat>
            <Date>20260615T162644+0200</Date>
          </ContentDate>
        </ResourceVersion>
      </SupportingResource>
    </CollateralDetail>
    <PublishingDetail>
      <Imprint>
        <ImprintIdentifier>
          <ImprintIDType>01</ImprintIDType>
          <IDValue>P15</IDValue>
        </ImprintIdentifier>
        <ImprintName>EDP Sciences &amp; Science Press</ImprintName>
      </Imprint>
      <Publisher>
        <PublishingRole>01</PublishingRole>
        <PublisherIdentifier>
          <PublisherIDType>01</PublisherIDType>
          <IDValue>P15</IDValue>
        </PublisherIdentifier>
        <PublisherName>EDP Sciences &amp; Science Press</PublisherName>
      </Publisher>
      <PublishingStatus>04</PublishingStatus>
      <PublishingDate>
        <PublishingDateRole>11</PublishingDateRole>
        <DateFormat>00</DateFormat>
        <Date>20260617</Date>
      </PublishingDate>
      <PublishingDate>
        <PublishingDateRole>01</PublishingDateRole>
        <DateFormat>00</DateFormat>
        <Date>20260617</Date>
      </PublishingDate>
      <PublishingDate>
        <PublishingDateRole>19</PublishingDateRole>
        <DateFormat>00</DateFormat>
        <Date>20260617</Date>
      </PublishingDate>
      <CopyrightStatement>
        <CopyrightYear>2026</CopyrightYear>
        <CopyrightOwner>
          <CopyrightOwnerIdentifier>
            <CopyrightOwnerIDType>06</CopyrightOwnerIDType>
            <IDValue>3052868830012</IDValue>
          </CopyrightOwnerIdentifier>
        </CopyrightOwner>
      </CopyrightStatement>
      <SalesRights>
        <SalesRightsType>01</SalesRightsType>
        <Territory>
          <RegionsIncluded>WORLD</RegionsIncluded>
        </Territory>
      </SalesRights>
    </PublishingDetail>
    <RelatedMaterial>
      <RelatedProduct>
        <ProductRelationCode>13</ProductRelationCode>
        <ProductIdentifier>
          <ProductIDType>03</ProductIDType>
          <IDValue>9782759840526</IDValue>
        </ProductIdentifier>
        <ProductIdentifier>
          <ProductIDType>15</ProductIDType>
          <IDValue>9782759840526</IDValue>
        </ProductIdentifier>
      </RelatedProduct>
    </RelatedMaterial>
    <ProductSupply>
      <Market>
        <Territory>
          <RegionsIncluded>WORLD</RegionsIncluded>
        </Territory>
      </Market>
      <MarketPublishingDetail>
        <PublisherRepresentative>
          <AgentRole>08</AgentRole>
          <AgentName>EDP Sciences &amp; Science Press</AgentName>
        </PublisherRepresentative>
        <MarketPublishingStatus>04</MarketPublishingStatus>
        <MarketDate>
          <MarketDateRole>01</MarketDateRole>
          <DateFormat>00</DateFormat>
          <Date>20260617</Date>
        </MarketDate>
      </MarketPublishingDetail>
      <SupplyDetail>
        <Supplier>
          <SupplierRole>03</SupplierRole>
          <SupplierIdentifier>
            <SupplierIDType>01</SupplierIDType>
            <IDValue>D1</IDValue>
          </SupplierIdentifier>
          <SupplierName>EDP Sciences</SupplierName>
        </Supplier>
        <ProductAvailability>20</ProductAvailability>
        <Price>
          <PriceType>04</PriceType>
          <PriceQualifier>05</PriceQualifier>
          <PriceCondition>
            <PriceConditionType>01</PriceConditionType>
            <PriceConditionQuantity>
              <PriceConditionQuantityType>02</PriceConditionQuantityType>
              <Quantity>1</Quantity>
              <QuantityUnit>00</QuantityUnit>
            </PriceConditionQuantity>
          </PriceCondition>
          <UnpricedItemType>01</UnpricedItemType>
          <CurrencyCode>EUR</CurrencyCode>
        </Price>
      </SupplyDetail>
    </ProductSupply>
  </Product>
</ONIXMessage>
