EDP Sciences 1775737932 20260409 fre

laboutique.edpsciences.fr-000601 03 01 01 000601 03 9782842541712 15 9782842541712 00 BA 02 1 mm 01 1 mm 08 1 gr 01 01 The CliniBook Clinical gene transfer state of the art 1 B26 01 A863 Odile Cohen-Haguenauer Cohen-Haguenauer, Odile Odile Cohen-Haguenauer Dr Odile Cohen-Haguenauer is the Coordinator of Clingene-NoE, the European Network for the Advancement of Clinical Gene Transfer and Therapy. 1 01 eng 00 588 03 24 Izibook:Subject Biologie médicale 24 Izibook:SubjectAndCategoryAndTags |Biologie médicale| 10 2011 MED047000 29 3169 01 610 01 616.904 06 05 00 This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation. 03 00 This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation. 02 00 This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of v... 21 00 06 01 https://laboutique.edpsciences.fr/produit/601/9782842542375/the-clinibook 01 00 03 02 https://laboutique.edpsciences.fr/system/product_pictures/data/009/981/647/original/The_Clinibook_CouvHD.jpg 17 14 20240913T172316+0200 15 00 04 02 01 E107 04 41712_som.pdf 05 0.75 06 699bc728a85e2c2c52c0ddbbbffd4fb1 https://laboutique.edpsciences.fr/extract/413?filename=41712_som.pdf&md5sum=699bc728a85e2c2c52c0ddbbbffd4fb1&size=783422&title=Sommaire+de+l%27ouvrage 17 14 20140822T131319+0200 16 00 04 01 https://laboutique.edpsciences.fr/extract/413/preview 01 P1 EDP Sciences 01 01 P1 EDP Sciences 17 avenue du Hoggar - PA de Courtaboeuf - 91944 Les Ulis cedex A http://publications.edpsciences.org/ 04 01 00 20121101 19 00 20121101 2026 06 3052868830012 01 WORLD 27 03 9782842542375 15 9782842542375 WORLD 08 EDP Sciences 04 01 00 20121101 03 01 D1 EDP Sciences 21 04 05 01 02 1 00 95.00 01 5.50 4.95 EUR laboutique.edpsciences.fr-R000082 03 01 01 R000082 00 ED E107 02 01 01 The CliniBook Clinical gene transfer state of the art 01 eng 08 589 03 22 8831994 17 16 00 06 01 https://laboutique.edpsciences.fr/flip_book/show/80 01 P1 EDP Sciences 01 01 P1 EDP Sciences 17 avenue du Hoggar - PA de Courtaboeuf - 91944 Les Ulis cedex A http://publications.edpsciences.org/ 02 01 000781 03 9782842542375 15 9782842542375 03 01 D1 EDP Sciences 45 03 laboutique.edpsciences.fr-000781 03 01 01 000781 03 9782842542375 15 9782842542375 10 EA E107 10 02 01 R000082 ED E107 1 01 01 The CliniBook Clinical gene transfer state of the art 1 B26 01 A863 Odile Cohen-Haguenauer Cohen-Haguenauer, Odile Odile Cohen-Haguenauer Dr Odile Cohen-Haguenauer is the Coordinator of Clingene-NoE, the European Network for the Advancement of Clinical Gene Transfer and Therapy. 1 01 eng 08 589 03 24 Izibook:Subject Biologie médicale 24 Izibook:SubjectAndCategoryAndTags |Biologie médicale| 10 2011 MED047000 29 3169 01 610 01 616.904 06 05 00 This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation. 03 00 This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation. 02 00 This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of v... 21 00 06 01 https://laboutique.edpsciences.fr/produit/601/9782842542375/the-clinibook 01 00 03 02 https://laboutique.edpsciences.fr/system/product_pictures/data/009/981/647/original/The_Clinibook_CouvHD.jpg 17 14 20240913T172316+0200 16 00 04 01 https://laboutique.edpsciences.fr/extract/413/preview 01 P1 EDP Sciences 01 01 P1 EDP Sciences 17 avenue du Hoggar - PA de Courtaboeuf - 91944 Les Ulis cedex A http://publications.edpsciences.org/ 04 01 00 20121101 19 00 20121101 2026 06 3052868830012 01 WORLD 13 03 9782842541712 15 9782842541712 WORLD 08 EDP Sciences 04 01 00 20121101 03 01 D1 EDP Sciences 20 04 05 01 02 1 00 65.99 01 5.50 3.44 EUR 04 06 01 02 1 00 231.99 01 5.50 3.44 EUR 01 04 06 01 02 1 00 255.99 01 5.50 13.35 USD 01